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Patient-Oriented Eczema Measure (POEM), a core instrument to measure symptoms in clinical trials: a Harmonising Outcome Measures for Eczema (HOME) statement

机译：以人为本的湿疹测量（POEM），一种在临床试验中测量症状的核心工具：湿疹协调成果测量（HOME）声明

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Background: The Harmonising Outcome Measures for Eczema (HOME) initiative has defined four core outcome domains for a core outcome set (COS) to be measured in all atopic eczema (AE) trials to ensure cross-trial comparison: clinical signs, symptoms, quality of life and longterm control.\udObjectives: The aim of this paper is to report on the consensus process that was used to select the core instrument to consistently assess symptoms in all future AE trials.\udMethods: Following the HOME roadmap, two systematic reviews were performed which identified three instruments that had sufficient evidence of validity, reliability, and feasibility to be considered for the final COS.\udResults: At the 4th international HOME meeting there was broad consensus among all stakeholders that the Patient-Oriented Eczema Measure (POEM) should be used as the core instrument (87.5% agreed, 9.4% unsure, 3.1% disagreed).\udConclusions: All relevant stakeholders are encouraged to use POEM as the chosen instrument to measure the core domain of symptoms in all future AE clinical trials. Other instruments of interest can be used in addition to POEM.
机译：背景：湿疹统一结果衡量方案（HOME）为所有特应性湿疹（AE）试验中要测量的核心结果集（COS）定义了四个核心结果域，以确保交叉试验比较：临床体征，症状，质量\ ud目标：本文的目的是报告共识过程，该共识过程用于选择在所有未来AE试验中一致评估症状的核心工具。\ ud方法：遵循HOME路线图，进行了两次系统评价结果表明：在第四届国际HOME会议上，所有利益相关者都普遍认为以患者为导向的湿疹措施（POEM） ）应该用作核心工具（同意的87.5％，不确定的9.4％，不同意的3.1％）。\ ud结论：鼓励所有相关的利益相关者使用POEM作为所选的工具nt在所有未来的AE临床试验中测量症状的核心范围。除POEM之外，还可以使用其他感兴趣的工具。

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